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Exclusion criteria were as follows: medical instability (see paragraph above and in addition this excluded patients who had frequent and/or repeated hospital admissions), previous unreliable behavior patterns, diabetes mellitus with fasting serum glucose140 mg/dL or treated with oral hypoglycemic agents or insulin endocrinopathies known to interfere with lipid metabolism, known genetic defects in lipid metabolism, previous or current carnitine therapy, lipid lowering drug therapy, class IV angina, liver failure, malignant hypertension, a high likelihood of an imminent living donor transplantation, and the presence of malignancies other than basal cell carcinomas of the skin

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However, the true advantage of ALCAR is not its absolute plasma concentration, but its lipophilicity