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UNSTABLE HEMOGLOBINS Amino acid substitutions that reduce solubility or increase susceptibility to oxidation result in unstable hemoglobins that precipitate, forming inclusion bodies injurious to the RBC membrane

The clinical relevance depends on the degree of elevation, persistence of abnormal results, and presence of other symptoms or laboratory abnormalities

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Solution conformation of proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry