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FIGURE 2 The genus Akkermansia is consistently enriched in human PD patients versus healthy controls, and the data corroborate recent findings in an A53T -synuclein Tg non-human primate model

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It is commonly known that the blastomeres apically-basally polarize as the embryo approaches implantation, resulting in the segregation of two different cell populations at the blastocyst stage: the inner cell mass and the outer trophectoderm

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As of January 2025, 18 registered strategies involving MSC-based treatments for lumbar intervertebral disc degeneration have been documented (Table 4), providing important references for the development of cell therapies for disc degeneration

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