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Why NAD+ declines with age Natural age-related decline : Decreased production Increased consumption (more cellular stress) Reduced recycling efficiency Mitochondrial dysfunction By age 50 : NAD+ levels about half of age 20 levels Impact : Everything from energy to recovery to longevity affected NAD+ boosting strategies Oral supplements (NMN, NR): Precursors that convert to NAD+ Variable absorption (5-30%) Modest NAD+ increase Affordable ($30-60/month) NAD+ IV therapy : Direct NAD+ infusion Immediate high levels Very expensive ($300-800 per session) Requires clinic visits NAD+ peptides : Stimulate natural NAD+ production Excellent bioavailability Sustained elevation Cost-effective ($50-150/month) Self-administered Best results : NAD+ peptides offer superior bioavailability and sustained effects vs oral supplements, at fraction of IV cost

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Enhanced Joint Function : By reducing pain and inflammation, knee injections can improve the knees range of motion and overall function

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A new 4 mg maintenance-dose arm is under investigation in the TRIUMPH program as a long-term post-titration dose

For example Charlotte who won a clinical negligence claim due to permanent damage caused by a late diagnosis and treatment