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Usually confirmed with a follow-up daytime test (MSLT)

The copper chelation component appears essential for this activity

Neonatal murine alveolar epithelial cells display a markedly stronger mitochondrial oxidative stress response to hyperoxia than their adult counterparts, indicating greater sensitivity of immature lung tissue to oxygen-induced ROS generation (Berkelhamer et al

It is often critically important to evaluate adrenal status in the patient with chronic fatigue because adrenal and thyroid function are so interdependent, and because increases in catacholamines and up-regulation of the sympathetic nervous system have been implicated in FMS, as previously discussed

The preserved dilation to ACh in MCA of Protandim-treated rats was prevented by inhibiting nitric oxide synthase (NOS) with L-NAME [100 M] and was absent in MCA from Nrf2 (/) knockout rats fed HS diet

NeuroImage 17 , 825841 (2002)