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Most frequently reported adverse drug reactions in pediatric patients (incidence 20%) were pyrexia, cough, diarrhea, rhinitis, abdominal pain, vomiting, headache, urticaria, nausea, rash, arthralgia, pruritus, fatigue, and pharyngitis

They enable the cells in the hormonal, immune, and nervous systems to communicate and coordinate their growth, death, regeneration, and functioning

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Gulzar et al

The CPT2 gene has a polymorphism found in about 1% of the population

Among them, IGFBP-5 is the most abundant in renal tissue, while IGFBP-3 is the most prevalent in circulation