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Mechanism of Action: The "Push-Pull" Effect

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A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007

It typically causes pain at the top of the leg (see image above) and will often begin at the buttock crease and refer down the leg

Finding practitioners familiar with these compounds may require research, as mainstream medical education typically does not cover research peptides

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