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Blood 138 , 11821193 (2021)

Eyayu, T., Zeleke, A

This triggers a cascade of effects: accelerated keratinocyte proliferation, increased desquamation (shedding of the outer layer), and stimulation of collagen synthesis in the dermis

doi: 10.1021/acs.jafc.2c01712

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If the benefits of fibrate therapy are indeed mitigated by fibrate-induced betaine deficiency, the use and safety of supplementing patients with betaine would need to be considered (127)