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In addition, hypoxic changes in mitochondrial metabolism lead to succinate accumulation and subsequent superoxide generation via reverse electron transport [9,10,11], though the degree of succinate accumulation may modulate these effects [12]

Moe-Lange, J

The results revealed that the irradiation group of animals experienced a reduction in body weight, followed by an increase

Molecular and cellular processes, such as myofibroblast/mesenchymal transition, myofibroblast activation and uncontrolled proliferation, endoplasmic reticulum stress, altered expression of growth factors, and oxidative stress, link PF to lung cancer and increase the risk of cancer development by 7%20% (Ballester et al., 2019)