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The minimum number of patients that must participate depends on the apparent probability of the adverse event of interest occurring, where rarer events demand a higher patient number to demonstrate a connection to the clinical trial sufficiently

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The major anticoagulant medication classes include: Unfractionated Heparin Low Molecular Weight Heparin Vitamin K Dependent Antagonists Direct Oral Anticoagulants Direct Thrombin Inhibitors Direct Factor Xa Inhibitors (14)

Lactate regulates autophagy through ROS-mediated activation of ERK1/2/m-TOR/p-70S6K pathway in skeletal muscle

This hypothesis is emphasized by the fact that other viral vaccines, e.g., hepatitis B recombinant vaccine or influenza vaccine, were also suspected to lead to transient facial nerve paralysis [8, 9]