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In the study by Wang et al (42), YAP, a key transcription factor in the Hippo signaling pathway known to be involved in various types of cancer (53), was found to associate with ACSL4 expression

doi:10.1152/jappl.2001.91.1.163

Thirdly, this study is limited to an animal model, so human cell-based or 3D models could be further utilized to evaluate the therapeutic potential of ST in humans in the future