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Formaldehyde forms various adducts with GSH, among them a cyclic adduct, BiGF 2 ((2S,7R)-7-(carboxymethylcarbamoyl)-5-oxo-9-thia-1,6-diaza-bicyclo [4.4.1] undecane-2-carboxylic acid), containing two equivalents of formaldehyde and one molecule of GSH

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230 The complex interactions of the gutliverbrain axis pose challenges for research but also offer potential targets for treating metabolic disorders