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Curcumins capacity to influence cytochrome P450 enzymes may alter the metabolism of chemotherapeutic drugs like paclitaxel and doxorubicin, potentially augmenting or diminishing their effectiveness (Peng et al., 2021)

Clinical trials have shown that GDNF does not significantly improve motor symptoms in PD patients and is associated with a higher incidence of serious adverse events (179)

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Cells were cultured for 4 days (mean SD, n = 3)

NSCLC cells were exposed to cycloheximide (CHX), a protein translation inhibitor with or without Tim-AIII