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It demonstrated preferential cytotoxicity and was more potent against the HCT-116 cell line, with an IC50 of 4.16 g/mL

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Furthermore, compared to CPZ treatment, there was a significant increase in MBP expression with CPZ + cytokine treatment (104.8% 8.27%, p = 0.015) and CPZ + LPS treatment (107.67% 9.0%, p = 0.008) (Figure 1D)

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These features suggest aberrant angiogenesis accompanies psoriasis pathogenesis 4

Higher concentrations may paradoxically reduce collagen birefringence, suggesting an inverse relationship between cell infiltration rate and matrix organization that warrants further mechanistic investigation