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Two small randomized, double-blind, placebo-controlled study found that once-daily oral L-histidine consumption for 4 to 12 weeks improved eczema scores (SCORAD) by ~34-39% in adults in 4 weeks and 49% in kids in 12 weeks, while placebo did not

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Green tea at high doses has been shown to reduce blood levels and, therefore, the effectiveness of the drug nadolol, a beta-blocker used for high blood pressure and heart problems

Drug Deliv Transl Res 11:353372 Dadari IK, Zgibor JC (2021) How the use of vaccines outside the cold chain or in controlled temperature chain contributes to improving immunization coverage in low-and middle-income countries (LMICs): a scoping review of the literature

That said, there are some important caveats: Lack of human clinical trials: Rodent models represent the bulk of the available data

MHY1485 treatment markedly reversed this downregulation (Figure S14F)