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The LCIG treatment involves a continuous infusion of a carboxymethylcellulose aqueous gel directly into the proximal jejunum via a percutaneous gastrojejunostomy tube, with delivery by a portable infusion pump (Olanow et al., 2014)

The superfamily of IGF binding proteins extends to a further ten proteins known as IGFBP-rPs that also bind IGFs, albeit at much lower affinities than the IGFBPs [23,24] (Table 1, Figure 2)

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Figueroa-Romero C, Hur J, Bender DE, Delaney CE, Cataldo MD, Smith AL et al (2012) Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis

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