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Warren|Hauser, Robert A.|Burdick, Daniel J.|Dhall, Rohit|de Marcaida, Joy Antonelle|Gil, Ramon A.|Kreitzman, David L.|Elmer, Lawrence W.|McGarry, Andrew|Kieburtz, Karl A Randomized Phase 3 Study Comparing P2B001 to its Components (LowDose ExtendedRelease Rasagiline and Pramipexole) and to Optimized Doses of Marketed ExtendedRelease Pramipexole in Early Parkinson's Disease Movement Disorders [08853185]

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In activated T cells, metabolic fitness and synthetic function has been directly linked to G6PD activity and ROS homeostasis by Ghergurovich and colleagues, who used a novel metabolite reporter and deuterium tracer assays to monitor cellular G6PD activity in the presence of a specific potent inhibitor of G6PD ( Figure 1A-3 )