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Description

PMN-MDSCs (CD11b+/Ly6C-/Ly6G+) numbers, in contrast, were reduced significantly in LLC tumors (p=0.03) but not in MC-38 tumors (Figures 2A and 2B)

The rippled -sheet position Glu85 in the FG loop is inserted into the SH2 pY pocket, where it forms an ionic interaction with SH2 residue Arg171, which is part of the conserved FLVRES motif and makes the most critical interaction with the phosphate group in pY peptide ligands (Fig