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The GHK-CU injection guide details various protocol approaches

When signaling was removed from all SHH-expressing cells, the NP was smaller in the mutant mice when compared to the control

10.1186/s12964-020-00637-3 54 GurungP.LukensJ

They found that their hydrogel promoted the differentiation of hBMSCs into NP cell-like phenotype and the synthesis of proteoglycan and type II collagen under hypoxia and mechanical stimulation