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In the folate/vitamin B12dependent mechanism, folate in the form of 5methyl tetrahydrofolate, derived from 5,10methylene tetrahydrofolate reductase catalyzed tetrahydrofolate modification, donates a methyl group to Hcy catalyzed by the vitamin B12dependent enzyme methionine synthase to form methionine

Additionally, it is commonly used in the treatment of pernicious anemia , a condition where the bodys ability to absorb B12 from food is impaired

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Rudman D, Feller AG, Nagraj HS, et al

Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S

From a coding standpoint, specificity is everything