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Calcabrini C, Maffei F, Turrini E, Fimognari C

Jiaming, L

Table 3 Biological limitations and complications associated with the current treatment approaches for PD

R.KindzelskiiA

10.3390/antiox9010021 27

Prolonged chronic stress and dysregulated glucocorticoid levels can disrupt the hippocampal neural circuitry, with characteristic structural alterations, including dendritic atrophy and remodeling, reduced dendritic spine density, and suppressed adult neurogenesis