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2J) and aspartate aminotransferase (AST) (Fig

Our mitochondriathe cells energy production centersare dependent on glutathione, which can cross mitochondrial membranes, minimize reactive oxygen species (ROS) buildup and hence maintain the redox balance inside cells

All 12 had already tried the only FDA-approved drug for it and it did not work

In order to develop effective therapeutic strategies, it is therefore essential to identify the subtype-specific molecular mechanisms underlying disease progression and resistance to chemotherapy

10.1080/10408398.2015.1032400 74 YangJ.JiaZ.XiaoZ.ZhaoJ.LuY.ChuL.et al (2021)