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Liu, S., Jacob, R., Piwnica-Worms, D

Beijing Solarbio Science & Technology Co., Ltd.)

Arginine and endothelial function

In OA animal models, oral or local administration of NAC has been observed to mitigate cartilage damage and pain, closely tied to its role in sustaining GSH levels and inhibiting ferroptosis (92)

Preclinical studies showed spinal nerve injury could lead to sustained neuronal upregulation and/or increased synaptic release of neuregulin-1, matrix metalloproteases, chemokine (C-C motif) ligand 2, fractalkine and its cognate receptor CXCR3

15 In 1900, catalase was recognized as a key enzyme in breaking down H 2 O 2 , marking an early discovery in antioxidant research