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Balabbigari N, Purewal J, Sakul N, Purewal A, Kankanala V, Califano T

Although hardly detectable in tissue, expression and activation of the matrix metalloproteases (MMPs) begins upon injury of the nervous system (Shubayev et al., 2006

The intensity threshold was 5000 units, target intensity was 20,000, and collision energy was ramped from 2059 eV

In aging, oligodendrocytes and OPCs also accumulate signs of oxidative DNA (mitochondrial and nuclear) damage, a feature which is commonly found in neurodegenerative diseases like Alzheimers disease and MS (Tse and Herrup, 2017)

Gonsalves N, Doerfler B, Zalewski A, Yang GY, Martin LJ, Zhang X et al

Methods 39 , 175191