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Description

found that NLRP3, gasdermin D (GSDMD), cleaved caspase-1, and cleaved IL-1 levels were upregulated in acute hypobaric hypoxia rats (6000 m, exposure for 3 days), suggesting that acute hypobaric hypoxia could activate the NLRP3/caspase-1 signaling pathway in heart tissue of acute hypobaric hypoxia-induced heart injury rats (Jia et al., 2023)

Epub 2013 Oct 11

ConCordix technology is designed to mirror the way we eat food, which includes chewing, swallowing and digesting

While preclinical studies demonstrate promising therapeutic potential, clinical outcomes may be influenced by factors such as patient variability, the TME, and tumor heterogeneity