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This can cause discolouration and other symptoms

In addition to the ApoER2 receptor, the megalin receptor mediates SEPP1 uptake by the kidney and thus provides a second targeting mechanism for selenium (27)

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In this study, we established a morphine-induced constipation mouse model, characterized by small intestinal dysfunction, including reductions in fecal output, fecal water content, the motility and the transit rate of small intestines