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Electrophoresis 18: 27142723

Waugh et al

Mitochondrial activity is practically downregulated by such a low level of oxygen

Methylglyoxal spontaneously reacts with glutathione to form a hemithioacetal adduct that is then acted on by glyoxalase-1 (GLO-1) to form S-D-lactoylglutathione and glyoxalase-2 (GLO-2) to form D-lactate

It has not only been shown to help wounds close faster with less chance of infection, but it also seems to be involved in healing ulcers and regenerating lung tissue [1, 2]