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Applications and prospects of intra-articular drug delivery system in arthritis therapeutics

Stanger MJ, et al

It restored intracellular antioxidants, preventing ROS from inducing NF-B activation

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Komenda, P

In preclinical models this dual mechanism produced greater weight loss than a maximal semaglutide dose, and in a Phase 2 diabetes trial higher survodutide doses reduced weight more than semaglutide though human superiority has not been formally established in head-to-head registration trials