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Under chronic stress, astrocytes adopt a neurotoxic A1 phenotype, characterized by downregulated autophagy genes (SQSTM1, MAP1LC3B) and loss of neurotrophic support

Sutomo R, Laosombat V, Sadewa AH, Yokoyama N, Nakamura H, Matsuo M et al

Hematoxylin - eosin (HE) staining indicated that SGD could alleviate liver tissue lesions, which was also confirmed by the recovery of liver index, ALT, and AST