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One of such metabolites, S-adenosylmethionine (SAM), serves as a universal methyl group donor required for proteins, RNAs, and DNA methylation

USA 109 , 55235528 (2012)

Shen Q, Huang H, Xie L, Hao X, Kayani SI, Liu H, Qin W, Chen T, Pan Q, Liu P, Tang K (2022) Basic helix-loop-helix transcription factors AabHLH2 and AabHLH3 function antagonistically with AaMYC2 and are negative regulators in artemisinin biosynthesis

The expiration of patents in 2028 may open the door for biosimilars, but the formidable barriers in the field of oncology for Pembrolizumab (Keytruda) are not easily shaken