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2021a) and most external organ of the human body forming the first barrier against chemical, physical and biological agents (Gegotek et al

Approaches evaluated to modulate or support glutathione status include: Precursor Support: Compounds such as N-acetyl cysteine (NAC), curcumin, and certain sulfur-containing or phytochemical-rich foods (e.g., broccoli, spinach) may support endogenous synthesis by providing precursors or upregulating synthesis pathways

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Its multi-target mechanisms also indicate therapeutic potential for metabolic, renal, and neurodegenerative disorders

In summary, TCM plays a significant role in the research of predicting acute mountain sickness, particularly in risk assessment, personalized management, and adjunctive therapy