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Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice

The ROS generated from aerobic respiration caused a cumulative oxidative damage in macromolecules, including lipids, DNA, and proteins, which subsequently lead to cells death (Scheibye-Knudsen et al., 2015), and affect the healthspan of numerous principal organ systems (Dai et al., 2014)

Phytomedicine 104, 154325

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4.6 or 8.6 W/m 2 , up to 20 h), as evidenced by their sensitivity to proteinase K treatment in the elution assay 183

This material is based upon work that is supported by the National Institute of Food and Agriculture, U.S