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doi: 10.1016/j.neuint.2016.06.009 152 MangiaS.SimpsonI

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Excessive iron accumulation may suppress the function and osteogenic differentiation of osteoblasts

Reviews that focus on phytochemicals emphasize mechanisms and preclinical efficacy, while nanoparticle reviews cover transport strategies and materials science, and few syntheses explicitly integrate nano-design variables with BBB transport outcomes for phytochemicals (26, 27)