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Overexpression of MGMT results in decreased response to alkylating agents such as TMZ, as evidenced by the significantly improved survival outcomes in the MGMT promotor methylated group (Median PFS 19 mo vs

doi: 10.1172/JCI119282

It can be used to treat chronic liver disease and is shown to improve liver function tests

However, more extensive studies must be conducted to confirm its long-term impact

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Many risk factors may be common to all three types of aging-related cataracts and, although cataracts often begin as a pure type, as they mature they typically become mixed cataracts