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Benefits for Gut Health: Potent anti-inflammatory effects in the GI tract Reduces symptoms in IBD, Crohns, and ulcerative colitis May improve microbiome balance Protects against epithelial barrier dysfunction How Its Used: KPV is often taken orally or as a rectal suppository for targeted local effects in the colon, especially in patients with colitis or inflammatory bowel flares

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Brain Res 1073:2537

These changes reduce production of proinflammatory cytokines such as IL-17 and promote anti-inflammatory functions in immune cells, including microglia (101)

Medical history and laboratory measurements within 3 months of each HRQoL measurement were abstracted from the medical chart

Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy