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Among rural Indian newborns with high rates of LBW, median (IQR) concentrations of tHcy have been reported as 11.7 (8.314.7) mol/L (31)

PubMed PMID: 23782218

This pressure can cause overgrowth of bones (osteophytes), joint swelling, fluid-filled sacs in the joints (synovial facet cysts), and a thickening of a key ligament in your spine (ligamentum flavum)