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Name: melanotan us peptides 2 (MT2) Melanotan II - Wikipedia
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Research Square Preprint2021 Jun

Because conformational induction of the hairpin is essential for Kme binding, a specific sequence context that will recapitulate these contacts is necessary

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Once internalized by the cell through the folate receptor (RFC1), MTX undergoes sequential glutamylation by folyl-polyglutamate synthase (FPGS), thus becoming MTX polyglutamates (MTX-PG 2-6 )

Sequencing libraries were generated using NEBNext UltraTM RNA Library Prep Kit for Illumina (NEB, USA) following manufacturers recommendations and index codes were added to attribute sequences to each sample