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After SCI, mitochondrial dysfunction can lead to the accumulation of ROS, which in turn activates JNK

It also downregulates lipogenic genes and lowers serum and hepatic TG and cholesterol in HFD mice (79)

When tumor cells undergo ferroptosis, they release damage-associated molecular patterns (DAMPs) such as high mobility group box 1 (HMGB1), adenosine triphosphate (ATP), and KRASG12D, which engage pattern recognition receptors (e.g., toll-like receptor 4,TLR4

The rs1332018 (A-63C) variant is located in the promoter region of GSTM3, and it has been shown to downregulate gene expression

Understanding the combined influence of BSE and gut microbiota on glucose regulation is essential for developing personalized interventions

In this study, baseline measurements revealed no significant differences based on donor sex or age