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1, mild response

After age 20, glutathione production declines steadily dropping by up to 50% by midlife

Aloe vera at a lower concentration of 2.5% or 10% has been shown to improve the proliferation rates of human dermal fibroblasts, and MSCs, whereas anthraquinone derivatives found in aloe vera extracts induce apoptosis in human hepatocellular carcinoma (HepG2) (12.5 mg/mL) by mediating mitochondrial activity and P53 pathway (Farid et al., 2022)

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Current knowledge shows that the pathogenesis of CIPN still remains elusive, mostly because there are several sites of involvement in the peripheral nervous system

With current CRC screening limitations, there is a need for less-invasive, cost-effective, and sensitive assays as an alternative to the existing gold standard of screening