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By targeting senescent cells and modulating mTOR locally, it reduces wrinkles, stimulates collagen, and supports autophagy without systemic exposure

Note that most animal studies use doses between 10 ng/kg and 10 g/kg, which corresponds to very small volumes in murine practice and imposes intermediate dilutions

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Following the injection of either vehicle or AMPT, animals were returned to open field boxes to track their locomotor activities for 30 min

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