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This variant included an additional arginine residue and featured an elongated structure at the N-terminal (by 13 amino acids), resulting in a protein composed of 83 amino acids, compared to the 70 amino acids found in natural IGF-1

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[DOI] [PMC free article] [PubMed] [Google Scholar] Chukwuma, I

Ultimately, this process induces CD8 + T cell infiltration into the TME to inhibit tumor growth (288)

This decline from 200 ng/mL to 80 ng/mL correlates directly with decreased regenerative capacity and visible signs of aging