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In cultured adipocytes and several mouse models, 5-Amino-1MQ reduced the NNMT activity marker 1-methylnicotinamide and was associated with changes in adiposity, glucose handling, liver histology and aged-muscle performance

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doi: 10.3390/cells10082032 162 AmoozgarZKloepperJRenJTayREKazerSWKinerEet al

J Hepatol 72(1): 183-196