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Accordingly, intervention concepts are gradually shifting from broadly restorative approaches toward more mechanism-based, phenotype-matched, and time-sensitive strategies

Earlier researchers established methods for evaluating the social vulnerability of communities

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AST also modulates the expression of pro-inflammatory cytokines and chemokines such as IL-6, IL-1, TNF-, vascular endothelial growth factors (VEGFs), and interferon- (IFN-) [56]