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JAMA Pediatr 170(11):10791086

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In conclusion, our study demonstrates that sulindac triggers autophagy-mediated apoptosis of GABAergic neurons via the PI3K/AKT/mTOR pathway, resulting in hyperactive behaviour in zebrafish larvae and mice (Fig

This process is regulated by both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), involving multiple transcription factors [3]

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