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The patience required during dose escalation is actually one of the most valuable aspects of the protocol

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The commenter also indicated that although Medicare Advantage is not a market-based system, the proposal would create an opportunity for negotiations to reflect market dynamics even if the immediate impact of the proposal is minimal due to the current extremely close correlation between the MS-DRG relative weights and the MA rates

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Severe gastroparesis or other serious gastrointestinal disorders, because tirzepatide slows stomach emptying, which can aggravate these conditions