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The phase III clinical trial in newly diagnosed GBM demonstrated a significant increase in overall survival by 4.9 months when combined with TMZ, in comparison to patients receiving TMZ alone (20.9 months and 16.0 months, respectively), resulting in the FDA approval of TTFields for GBM in 2015 (29)

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J Virol :JVI0155021 Wen W, Li X, Yin M, Wang H, Qin L, Li H, Liu W, Zhao Z, Zhao Q, Chen H et al (2021) Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3

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