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Cells become sickled due to reduced hydration status and hemolytic anemia

Roberti, A., Fernndez, A

In addition to its native roles, glutathione has several important applications in scientific research including protein purification, protein refolding, and cell culture

For instance, the transcripts of polyoma simian virus 40 (SV40) and adenovirus, DNA viruses that replicate in the nucleus, were shown to be extensively modified 65,66