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Despite these promising findings, current evidence remains largely preclinical

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Frias JP, Deenadayalan S, Erichsen L, Knop FK, Lingvay I, Macura S, et al

Both selective AMYR agonists, and dual CTR and AMYR agonists such as sCT 5,6,7 , have demonstrated efficacy in controlling appetite and body weight, however this is not seen with a CTR-selective agonist 9