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Glutamate (Glu) is an important excitatory amino acid neurotransmitter, with the highest content in brain tissue, released by about 3% of synapses, and acts on postsynaptic membrane receptors, mainly the N-methyl-D-aspartate receptor subtype (NMDAR), to exert excitatory regulatory effects

Treatment with Apocynin or Picrorhiza kurroa decreases clinical and pathological features of parkinsonism Abstract This study evaluates the therapeutic efficacy of the NADPH oxidase inhibitor apocynin, isolated as principal bioactive component from the medicinal plant Picrorhiza kurroa, in a marmoset MPTP model of Parkinsons disease (PD)

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