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By integrating these mechanistic insights with emerging data on how disrupted lipid and glucose metabolism amplify immune dysregulation, the review underscores the interplay between metabolic and inflammatory pathways in exacerbating tissue injury across these organs

Antibiotics eliminated the efficacy of metformin against intestinal ferroptosis in IIRI Metformin-treated IIRI mice were administered antibiotics to disrupt their gut microbiota

Nickel, P

The level of mitochondrial interleukin-1 (IL-1) was measured in duplicate samples using a commercial enzyme-linked immunosorbent assay (ELISA) kit (IL-1 ELISA kit, R&D Systems